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      WebLab3: Exercise 2
CELL DIVISION (MITOSIS)


Objectives:
  • Describe four everyday events occurring in your body that are based on mitosis.
  • Explain the importance of accurate replication of a cell's genetic make-up prior to mitosis.
  • State the relationship between genes and DNA
  • Explain the relationship between DNA and chromosomes
  • Draw a diagram of the cell cycle and 1) label the following phases: G1, S, G2, and M; and 2) explain what occurs in each phase.
  • Define the terms: chromatid, centromere, kinetochore, spindle fibers, cytokinesis.
  • Draw and label the stages of mitosis in a cell with a diploid number of 4.
  • Submit a poster construction project illustrating the stages of mitosis.
Materials:
  • A computer, a printer, and an ISP (Internet Service Provider).
  • Construction paper, magic markers, pipe cleaners (your instructor will illustrate these in class), scissors, transparent tape.
Methods:
  1. Read the Background Information to help prepare you for the content of this exercise.
  2. Study The Cell Cycle Diagram noting the positions of the phases of the cycle.
  3. Go to The Mitosis Animation, sponsored by the University of Texas, and observe the process in a continous sequence. Note that after the video has played, you can control the video using your mouse and the controls at the bottom of the quick-time player. Go through the process slowly observing all changes in chromosomes and related organelles.
  4. Study the Mitosis Illustrations. Click on each of the phases of mitosis and compare them with the animation you just observed.
  5. Neatly carry out the following project utilizing poster board, magic markers, and pipe cleaners:
    • Draw diagrams illustrating the stages of mitosis in a cell with a diploid number of 4.
    • Use magic markers to illustrate all cellular organelles except for the chromosomes.
    • Use the pipe cleaners to simulate the chromosomes in the nucleus and their movements during mitosis.
    • The following cellular organelles should be visible, where appropriate, in the various mitotic stages:
      • cell membrane
      • nuclear membrane
      • chromatin
      • centrioles
      • chromosomes
      • chromatids
      • spindle fibers
      • centromere
      • asters
      • cleavage furrow
      • nucleolus
    • Submit your constructed mitosis project in class.
    • There are two technical errors in the mitosis animation. You can get extra credit if you find at least one of them and submit your comments to me through the contact page.
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